Malignancy in dermatomyositis: a mono-centric retrospective study of 134 patients in China and a potential predictive model.

Frontiers in medicine(2023)

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摘要
Positivity of anti-TIF1γ and anti-Mi2 autoantibodies are highly indicative of malignancies while the role of anti-NXP2 autoantibody in MADM in the Chinese population remains unclear. The phenotypes of malignancies can be predicted through the model and the predictive power is sufficient. More attention should be paid to malignancies screening in patients with aberrant tumor biomarkers but no malignancies, particularly digestive system, nasopharyngeal, and lung malignancies in patients with dermatomyositis but without malignancies.
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关键词
dermatomyositis,malignancies,autoantibody,tumor biomarkers,predictive model,receiver operating characteristic curve
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