Analysis of mRNA-miRNA interaction network reveals the role of CAFs-derived exosomes in the immune regulation of oral squamous cell carcinoma.

BMC cancer(2023)

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摘要
CAFs-Exo was found to be involved in tumor immune regulation through hsa-miR-139-5p, ACTR2 and EIF6, while PIGR, CD81, UACA and PTTG1IP may be potentially effective targets for the treatment of OSCC in the future.
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关键词
Cancer-associated fibroblasts, Exosomes, Oral squamous cell carcinoma, mRNA-miRNA interaction network analysis, Immunomodulation
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