Synergistic Chemopreventive Effects of a Novel Combined Plant Extract Comprising Gallic Acid and Hesperidin on Colorectal Cancer.

Szu-Jung Chen, Jui-Hua Lu,Chih-Cheng Lin, Shao-Wei Zeng,Jia-Feng Chang,Yuan-Chiang Chung,Hsiang Chang,Chih-Ping Hsu

Current issues in molecular biology（2023）

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摘要

Gallic acid and hesperidin exert synergistic effects on cell growth, spheroids, and stemness of CRC and may serve as a potential chemopreventive agent. Further testing for the safety and effectiveness of the combined extract in large-scale randomized trials is required.

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gallic acid, hesperidin, colorectal cancer, cell cycle, cancer stemness, spheroids

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