Validating a novel three-times-weekly post-hemodialysis ceftriaxone regimen in infected Indigenous Australian patients-a population pharmacokinetic study.

Danny Tsai, Betty B Zam, Carleigh Tongs,Fabian Chiong,Cherian Sajiv,Basant Pawar,Aadith Ashok, Brynley P Cooper,Steven Y C Tong,Sonja Janson,Steven C Wallis,Jason A Roberts,Suzanne L Parker

The Journal of antimicrobial chemotherapy（2023）

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摘要

A novel 2 g three-times-weekly post-dialysis ceftriaxone regimen can be recommended for a bacterial infection with an MIC ≤1 mg/L. A 1 g three-times-weekly post-dialysis regimen is recommended for those with serum bilirubin ≥10 µmol/L. Administration of ceftriaxone during dialysis is not recommended.

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infected indigenous australian patients—a,three-times-weekly,post-hemodialysis

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