Age-Related Subgingival Colonization of Aggregatibacter actinomycetemcomitans , Porphyromonas gingivalis and Parvimonas micra -A Pragmatic Microbiological Retrospective Report.

The aim of this study was to compare data about the prevalence and proportions of the bacterial species , , and in periodontitis pocket samples collected from young, <35 years, and old, >35-year-old patients, YP and OP, respectively. The results from the analyses of a total of 3447 subgingival plaque samples analyzed for clinical diagnosis purposes by cultivation regarding the proportions of these species were collected from a database and elucidated. The prevalence of A. was found to be more than twice as high (OR = 2.96, 95% CI; 2.50-3.50) in samples from the younger (42.2%) than the older group (20.4%) ( < 0.001). The prevalence of was significantly lower in samples from the younger age group (OR = 0.43, 95%) ( < 0.001), whereas was similarly distributed (OR = 0.78, 95%) in the two age groups ( = 0.006). A similar pattern was noticed for and when high proportions (>50%) of the samples of these bacterial species were elucidated. In contrast, the proportion of samples containing >50% with was lower compared with the two other bacterial species. Furthermore, it was noted that the proportion of samples from old patients containing in combination with was almost three times higher than in samples when was replaced by . In conclusion, showed an increased presence and proportion in samples from young patients compared with the old patients, while was similarly distributed in the two age groups. showed an increased presence and proportion in samples from old patients compared with the young patients.