Biomarkers of immunothrombosis and polymorphisms of IL2, IL6, and IL10 genes as predictors of the severity of COVID-19 in a Kazakh population.

Assiya Yessenbayeva,Bakytbek Apsalikov,Meruyert Massabayeva,Maksut Kazymov,Aizhan Shakhanova,Zhanna Mussazhanova,Irina Kadyrova, Nurlan Aukenov,Nurlan Shaimardanov

PloS one（2023）

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摘要

The results of our study confirm that D-dimer, fibrinogen, and CRP are biomarkers of inflammation and hypercoagulation that serve as predictors of immunothrombosis affecting the severity of COVID-19. D-dimer is also associated with IL10 rs1800872 gene polymorphism in the Kazakh population with severe COVID-19.

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il10 genes,immunothrombosis,il6,il2

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