Whole-Exome sequencing analysis identified TMSB10/TRABD2A locus to be associated with carfilzomib-related cardiotoxicity among patients with multiple myeloma.

Marwa Tantawy,Guang Yang, Raghunandan Reddy Algubelli,Gabriel DeAvila,Samuel M Rubinstein,Robert F Cornell,Michael G Fradley,Erin M Siegel,Oliver A Hampton,Ariosto S Silva,Daniel Lenihan,Kenneth H Shain,Rachid C Baz,Yan Gong

Frontiers in cardiovascular medicine（2023）

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摘要

We identified a missense SNP rs7148 in the as associated with CFZ-CVAE in MM patients. More investigation is needed to understand the underlying mechanisms of these associations.

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关键词

multiple myeloma,tmsb10/trabd2a locus,cardiotoxicity,whole-exome,carfilzomib-related

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