Diagnostic Accuracy of Brain Natriuretic Peptide and N-terminal-pro Brain Natriuretic Peptide to Detect Complications of Cardiac Transplantation in Adults: A Systematic Review and Meta-Analysis

•We report no significant association between BNP or NT-proBNP and significant acute cellular rejection of grade 3A or higher.•We report no strong associations between BNP or NT-proBNP and cardiac allograft vasculopathy or antibody mediated rejection.•BNP and NT-proBNP lack sufficient sensitivity and specificity to reliably predict adverse outcomes following cardiac transplantation.