Comparison of sexual function in females after reproductive organ sparing versus non-reproductive organ sparing radical cystectomy

You have accessJournal of UrologyCME1 Apr 2023PD26-04 COMPARISON OF SEXUAL FUNCTION IN FEMALES AFTER REPRODUCTIVE ORGAN SPARING VERSUS NON-REPRODUCTIVE ORGAN SPARING RADICAL CYSTECTOMY Sajya Singh, Natasha Gupta, Shirley Wang, Isabella Florissi, Max Kates, Trinity Bivalacqua, and Sunil Patel Sajya SinghSajya Singh More articles by this author , Natasha GuptaNatasha Gupta More articles by this author , Shirley WangShirley Wang More articles by this author , Isabella FlorissiIsabella Florissi More articles by this author , Max KatesMax Kates More articles by this author , Trinity BivalacquaTrinity Bivalacqua More articles by this author , and Sunil PatelSunil Patel More articles by this author View All Author Informationhttps://doi.org/10.1097/JU.0000000000003304.04AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail Abstract INTRODUCTION AND OBJECTIVE: Given recent data, reproductive organ sparing (ROS) radical cystectomy is a safe and effective treatment for bladder cancer in select women. In this study, we sought to better understand sexual function outcomes in females who underwent a ROS versus a non-reproductive organ sparing (non-ROS) radical cystectomy for the treatment of bladder cancer. METHODS: A cross-sectional questionnaire was administered in April 2022 to eligible participants selected from a retrospective single-institution cohort of female patients with a primary bladder malignancy who underwent radical cystectomy between 2016-2020. The study questionnaire included the short form of the Female Sexual Function Index (FSFI-6), a validated evaluation tool for diagnosing female sexual dysfunction (FSD) (score ≤19). Satisfaction with sex life was reported on a Likert scale with 5=dissatisfied and 1=satisfied. Bother with lack of sexual activity was reported as 4=a lot and 1=not at all. RESULTS: Among eligible patients (n=70), 45 women (64%) completed the questionnaire on average 3.1±1.0 and 3.4±1.4 years post-cystectomy for the ROS and non-ROS groups, respectively (p=0.59). Advanced-stage bladder cancer (≥pT3) was not statistically more prevalent in non-ROS (36%) compared to ROS patients (19%, p=0.25). Before surgery, significantly more women were sexually active in the ROS group (61%) than non-ROS (21%, p=0.01); however, post-cystectomy, this difference was not observed (29% vs. 21%, p=0.59). There was a trend towards more FSD among ROS patients by FSFI-6 (57% vs. 33%, p=0.49). In both the ROS and non-ROS groups, patients who were not sexually active reported low levels of bother regarding the absence of sexual activity (1.8±1.0 vs. 1.8±1.1, p=0.86). CONCLUSIONS: Within our limited cross-sectional cohort, we identified a higher prevalence of FSD in the ROS group, although this finding was not statistically significant. Consideration of patient-specific values when discussing post-operative sexual function is essential as most non-sexually active patients denied feeling concerned by a lack of sexual activity. Further research is needed to better understand the factors impacting post-cystectomy sexual function in women and to investigate interventions targeting the psychoeducational components of sexual health. Source of Funding: None © 2023 by American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetails Volume 209Issue Supplement 4April 2023Page: e736 Advertisement Copyright & Permissions© 2023 by American Urological Association Education and Research, Inc.MetricsAuthor Information Sajya Singh More articles by this author Natasha Gupta More articles by this author Shirley Wang More articles by this author Isabella Florissi More articles by this author Max Kates More articles by this author Trinity Bivalacqua More articles by this author Sunil Patel More articles by this author Expand All Advertisement PDF downloadLoading ...