Mp75-09 rural and urban genitourinary cancer incidence and mortality in the pennsylvania cancer registry from 1990-2019

You have accessJournal of UrologyCME1 Apr 2023MP75-09 RURAL AND URBAN GENITOURINARY CANCER INCIDENCE AND MORTALITY IN THE PENNSYLVANIA CANCER REGISTRY FROM 1990-2019 Jonathan Pham, Ahmad Alzubaidi, Tullika Garg, and Jay Raman Jonathan PhamJonathan Pham More articles by this author , Ahmad AlzubaidiAhmad Alzubaidi More articles by this author , Tullika GargTullika Garg More articles by this author , and Jay RamanJay Raman More articles by this author View All Author Informationhttps://doi.org/10.1097/JU.0000000000003349.09AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail Abstract INTRODUCTION AND OBJECTIVE: Cancer mortality is steadily rising in rural communities in the United States compared to urban counterparts. The underlying causes of these disparities are complex and multifactorial. Our objective was to describe trends in rural and urban incidence and mortality of genitourinary (GU) cancers in the Pennsylvania Cancer Registry. METHODS: We conducted a retrospective review of age-adjusted incidence and mortality rates of GU (prostate (PC), bladder (BC), and kidney (KC)) cancers by county from 1990-2019. Counties were designated as urban or rural using the Center for Rural Pennsylvania’s population-density based definition defined as 284 people per square mile using 2019 county census data. In Pennsylvania, 48 rural counties and 19 urban counties were identified. Joinpoint regression was used to model average annual percent changes (AAPC) in age-adjusted incidence and mortality rates in urban and rural counties. RESULTS: From 1990-2019, overall age-adjusted GU cancer incidence significantly decreased in rural (AAPC -7.5%, p=0.04) and in urban counties (-6.6%, p=0.02). For PC, age-adjusted incidence decreased in rural counties by -10.5% (p=0.02) and in urban counties by -9.1% (p=0.01). Age-adjusted incidence of BC was unchanged for both urban and rural counties. KC incidence increased in both rural counties (AAPC=+11.2, p=0.002) and in urban counties (AAPC=+9.3%, p=0.01).Overall GU cancer age-adjusted mortality decreased in rural counties (AAPC=-11.6, p=0.047) and in urban counties (AAPC -12.2, p=0.01). PC mortality for rural and urban counties decreased at similar rates (AAPC -15.5, p=0.03 and -15.4, p=0.02, respectively). Age-adjusted mortality for BC was unchanged for rural and urban counties over the study period. KC mortality in urban counties decreased (AAPC -6.9% p=0.03), while mortality in rural counties remained stable. CONCLUSIONS: From 1990-2019, overall GU cancer incidence and mortality have decreased in both rural and urban Pennsylvania counties. Across all counties, PC incidence and mortality have decreased, and BC incidence and mortality have remained stable. KC incidence increased across all counties; however, mortality remained stable in rural counties. These data may inform targeted interventions to improve outcomes for specific GU cancers in rural areas. Source of Funding: N/A © 2023 by American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetails Volume 209Issue Supplement 4April 2023Page: e1082 Advertisement Copyright & Permissions© 2023 by American Urological Association Education and Research, Inc.MetricsAuthor Information Jonathan Pham More articles by this author Ahmad Alzubaidi More articles by this author Tullika Garg More articles by this author Jay Raman More articles by this author Expand All Advertisement PDF downloadLoading ...