Estimation of the preanalytical activation of the contact system in coagulation tubes.

Søren Risom Kristensen,Jørgen Brodersen Gram,Jette Nybo,Johannes Jakobsen Sidelmann,Yaseelan Palarasah

Thrombosis research（2023）

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摘要

•Preanalytical activation of the contact system may interfere with coagulation assays•Different sample tubes may activate the contact system differently•Activation can be quantified by Cleaved H-Kininogen and Fast form α2−Macroglobulin•Activation was much higher in Vacutainer tubes than in Monovette tubes•Tubes with a low contact activation are preferable for some coagulation assays

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