Platform trials to evaluate the benefit-risk of COVID-19 therapeutics: Successes, learnings, and recommendations for future pandemics

Joan Buenconsejo,Ran Liao,Junjing Lin,Pritibha Singh,Freda Cooner,Samiran Ghosh,Margaret Gamalo,Estelle Russek-Cohen,Névine Zariffa

Contemporary clinical trials（2023）

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摘要

These trials deployed during the COVID-19 pandemic demonstrate how to achieve both speed and quality of evidence generation regarding clinical benefit (or not) of existing therapies to treat new pathogens in a pandemic setting. As a group, these trials identified treatments that worked, and many that did not, in a matter of months.

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关键词

COVID-19,Platform trials,Repurposed drugs

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