Guianensin, a Simulium guianense salivary protein, has broad anti-hemostatic and anti-inflammatory properties.

Paola Carolina Valenzuela-Leon,Andrezza Campos Chagas,Ines Martin-Martin,Adeline E Williams,Markus Berger,Gaurav Shrivastava,Andrew S Paige,Michalis Kotsyfakis,Lucas Tirloni,Eric Calvo

Frontiers in immunology（2023）

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摘要

The information generated by this work highlights the biological functionality of Guianensin as an antithrombotic and anti-inflammatory protein that may play significant roles in blood feeding and pathogen transmission.

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关键词

blood feeding, black fly, saliva, arthropod, enzyme inhibitor, anticoagulant

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