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Aspirin delays the onset of hypertensive disorders of pregnancy among nulliparous pregnant women: A secondary analysis of the ASPIRIN trial.

Avinash Kavi,Matthew K Hoffman,Manjunath S Somannavar,Mrityunjay C Metgud,Shivaprasad S Goudar,Janet Moore,Eleanor Nielsen,Norman Goco,Elizabeth M McClure,Adrien Lokangaka,Antoinette Tshefu,Melissa Bauserman,Musaku Mwenechanya,Elwyn Chomba,Waldemar A Carlo,Lester Figueroa,Nancy F Krebs,Saleem Jessani,Sarah Saleem,Robert L Goldenberg,Prabirkumar Das,Archana Patel,Patricia L Hibberd,Fabian Esamai,Sherri Bucher,Marion Koso-Thomas,Robert Silver,Richard J Derman

BJOG : an international journal of obstetrics and gynaecology（2023）

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摘要
In this secondary analysis of a study of low-risk nulliparous singleton pregnancies, early administration of LDA resulted in lower rates of preterm HDP and delivery before 34 and 37 weeks but not in the overall rate of HDP. These results suggest that LDA works in part by delaying HDP.
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aspirin, hypertensive disorders of pregnancy, low- and middle-income countries, nulliparous, preterm
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