Early biochemical and radiographic response after one cycle of [ 177 Lu]Lu-PSMA I&T radioligand therapy in metastatic castration-resistant prostate cancer patients.

Wojciech Cytawa,Robin Hendel,Bartłomiej Tomasik,Franz-Xaver Weinzierl,Thorsten Bley,Jacek Jassem,Andreas Schirbel,Andreas K Buck,Ralph A Bundschuh,Philipp E Hartrampf,Rudolf A Werner,Constantin Lapa

European journal of nuclear medicine and molecular imaging（2023）

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摘要

In this retrospective cohort, there was no association between early PSMA PET radiographic response and overall survival; hence, treatment should not be prematurely discontinued. In contrast, early PSA progression after one cycle of [Lu]Lu-PSMA I&T RLT was an indicator of overall progression and poor clinical outcome.

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