A Th1-like CD4 + T-cell Cluster That Predicts Disease-free Survival in Early-stage Lung Cancer.

Akitoshi Yanagihara,Satoshi Yamasaki,Kosuke Hashimoto,Ryo Taguchi,Tetsuya Umesaki,Hisao Imai,Kyoichi Kaira,Hiroyuki Nitanda,Hirozo Sakaguchi,Hironori Ishida,Kunihiko Kobayashi,Katsuhisa Horimoto,Hiroshi Kagamu

Cancer research communications（2023）

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摘要

Peripheral Th7R, a Th1-like CD4 T-cell cluster reflecting priming status in draining LNs and immune status in the tumor microenvironment, predicts disease-free survival after complete resection and has significant clinical relevance in selecting appropriate therapeutic interventions in patients with early-stage lung cancer.

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关键词

lung cancer,cluster,t-cell,disease-free,early-stage

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