Reference Interval Harmonization: Harnessing the Power of Big Data Analytics to Derive Common Reference Intervals across Populations and Testing Platforms.

Mary Kathryn Bohn,Dana Bailey,Cynthia Balion,George Cembrowski,Christine Collier,Vincent De Guire,Victoria Higgins,Benjamin Jung, Zahraa Mohammed Ali,David Seccombe,Jennifer Taher,Albert K Y Tsui,Allison Venner,Khosrow Adeli

Clinical chemistry（2023）

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摘要

We report a novel data-driven approach for RI harmonization. Findings support feasibility of RI harmonization for several analytes; however, some presented challenges, highlighting limitations that need to be considered in harmonization and big data analytics.

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关键词

reference interval harmonization,common reference intervals,big data analytics,testing

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