Differences in the Ultrastructure of Neurons in the Spinal Ganglion and Dorsal Rootlet Between Rats Treated with Cisplatin Only versus Co-administration with a Sphingosine 1-Phosphate Receptor 2 Agonist in Attenuating Neuropathy and Allodynia.

Together with our previous study, showed that CYM-5478 attenuated neuropathy and allodynia in a rat model of cisplatin-induced neuropathy, these results suggest S1P2 agonists as a potential approach for treatment of cancer due to reduction of side-effects of cisplatin. This article is protected by copyright. All rights reserved.