Analysis of various ATP-binding cassette transporters revealed quantification of ABCB4 as a potential diagnostic tool in primary sclerosing cholangitis (PSC).

Cornelia Thoeni,Catia T Perciani,Diana Nakib,Damra Camat,Ian D McGilvray,Sonya A MacParland,Sandra Fischer

Histopathology（2023）

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摘要

Our study concluded that altered ABCB4 expression is specifically seen in liver specimens of PSC patients. Therefore, quantitative ABCB4 analysis may be an additional useful tool for the histopathological diagnosis of PSC to distinguish this entity from other cholangiopathies.

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cholangitis,cassette transporters,<scp>atp</scp>‐binding,potential diagnostic

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