Retrospective neuropathological diagnosis of TDP-43 proteinopathies: Factors affecting immunoreactivity of phosphorylated TDP-43 in fixed post-mortem brain tissue

The data that support the findings of this study are available from the corresponding author upon reasonable request. Figure S1. Amyloid-beta, phosphorylated PHF tau and phosphorylated alpha-synuclein staining of the superior temporal gyrus from a case of mixed AD/DLB donated in 2005. Panels (A–C) show staining from the original diagnostic block with short fixation, Panels (D–F) show staining from a block subjected to extended formalin fixation, and Panels (G–I) show staining of sections taken from a long-term FFPE block. Magnification 400× (40× objective; 10× eyepiece). Scale bars: 50 μm. Table S1. Source, type, antigen retrieval method, and dilution of primary antibodies used in immunohistochemical staining. CC1, cell conditioning solution 1; HIER, heat-induced epitope retrieval. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.