Incidence of serum antibodies to xenoantigens on triple-knockout pig cells in different human groups.

Songzhe He,Tao Li,Hao Feng,Jiaxiang Du,David K C Cooper,Hidetaka Hara,Hongtao Jiang,Dengke Pan,Gang Chen,Yi Wang

Xenotransplantation（2023）

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摘要

Human sera contain IgM antibodies against unknown pig xenoantigens expressed on TKO/hCD55 pPBMCs. Although not confirmed in the present study, the targets for these antibodies may include swine leukocyte antigens.

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antibodies, gene editing, pig, xenoantigens

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