Insufficient measles antibody protection in 6-month-old Malawian infants: Reconsider vaccination schedule?

Silvia Baroncelli,Clementina Maria Galluzzo,Stefano Orlando,Richard Luhanga,Robert Mphwere,Thom Kavalo,Roberta Amici,Marco Floridia,Mauro Andreotti,Fausto Ciccacci,Maria Cristina Marazzi,Marina Giuliano

Tropical medicine & international health : TM & IH（2023）

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摘要

Measles vaccination is currently recommended at 9 months, since maternal antibodies are supposed to protect infants until that age. In this study of 6-month-old Malawian infants 98.3% (58/59) had non-protective IgG levels against measles, irrespective of HIV exposure. Anticipating the first dose at 6 months could be considered.

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infants, Malawi, maternal protection, measles, vaccination schedule

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