CircRNA-SCAF8 Promotes Vascular Endothelial Cell Pyroptosis by Regulating the Mir-93-5p/txnip Axis.

Bing Wang,Xinyu Yu,Tianchi Chen,Chenyang Qiu, Yangyan He,Wei Lu,Xiangtao Zheng,Ziheng Wu

Zhejiang Daxue xuebao Yixue ban（2023）

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摘要

CircRNA-SCAF8/miR-93-5p/TXNIP axis is involved in the regulation of pyroptosis in HUVECs under high glucose and may be a new therapeutic target for diabetic vascular diseases.

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关键词

Circular RNA-SCAF8,Diabetes mellitus type 2,Human umbilical vein endothelial cells,MiR-93-5p,Pyroptosis,Thioredoxin interacting proteins

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