miR-21-5p promotes NASH-related hepatocarcinogenesis.
Liver international : official journal of the International Association for the Study of the Liver（2023）
摘要
Hsa-miR-21-5p is a key inducer of whole-spectrum NAFLD progression, from simple steatosis to NASH and NASH-associated carcinogenesis. The inhibition of hsa-miR-21-5p, leading to a pro-metabolic profile, might constitute an appealing therapeutic approach to ameliorate NASH and prevent progression towards HCC.
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关键词
hepatocarcinogenesis
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