Correlation of ex vivo cytokine secretion profiles with scoring indices in ulcerative colitis.

Marija Podolski,Lidija Požgaj,Ivan Faraho,Adriana Petrinić Grba,Daniela Belamarić,Andrea Paravić Radičević,Martina Bosnar,Marija Crnčević Urek,Aleksandar Čubranić,Sanda Mustapić,Brankica Mijandrušić-Sinčić,Marko Banić,Vesna Eraković Haber

European journal of clinical investigation（2023）

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摘要

Our findings suggest that choosing biopsies from donors with MES = 2-3 and UCEIS = 2-6 from areas with no bleeding and no superficial and/or deep ulcers could enable a deeper insight into the cytokine profile of the inflamed tissue and represent a better tool for studying potential therapeutic targets and evaluation of novel therapies.

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关键词

cytokines, IBD, endoscopic score, MES, UCEIS, ulcerative colitis

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