PD02-10 EVALUATING THE DIAGNOSTIC PERFORMANCE OF BIPARAMETRIC MAGNETIC RESONANCE IMAGING AND MULTIPARAMETRIC MAGNETIC RESONANCE IMAGING IN MUSCLE-INVASIVE BLADDER CANCER

You have accessJournal of UrologyBladder Cancer: Invasive I (PD02)1 May 2024PD02-10 EVALUATING THE DIAGNOSTIC PERFORMANCE OF BIPARAMETRIC MAGNETIC RESONANCE IMAGING AND MULTIPARAMETRIC MAGNETIC RESONANCE IMAGING IN MUSCLE-INVASIVE BLADDER CANCER Qiang Lyu, Xiao Yang, Qiang Cao, and Peikun Liu Qiang LyuQiang Lyu , Xiao YangXiao Yang , Qiang CaoQiang Cao , and Peikun LiuPeikun Liu View All Author Informationhttps://doi.org/10.1097/01.JU.0001008836.73392.92.10AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail Abstract INTRODUCTION AND OBJECTIVE: Vesical Imaging-Reporting and Data System (VI-RADS) based on multiparametric magnetic resonance imaging (mp-MRI) performed well in diagnosing muscle-invasive bladder cancer (MIBC). In addition, the final VI-RADS score cannot be accurately determined if only using T2-weighted imaging (T2WI) and diffusion-weighted imaging (DWI) images. Our goal was to evaluate whether biparametric MRI (bp-MRI) shared the same good diagnostic performance as mp-MRI in the diagnosis of MIBC, and to explore the most suitable bp-MRI criterion. METHODS: A retrospective study enrolled 447 patients with bladder cancer who had preoperative mp-MRI images. The collected images were split into two sets: Set 1 (bp-MRI) and Set 2 (mp-MRI). Two qualified readers evaluated the tumor category on T2WI, DWI and dynamic contrast enhanced imaging. Set 2 was evaluated according to the VI-RADS protocol, while Set 1 was evaluated based on four bp-MRI criteria: If T2WI category 3 with DWI category 2, the VI-RADS score is 2 of Criterion 1 and Criterion 2, 3 of Criterion 3 and Criterion 4. If T2WI category 3 with DWI category 3, the VI-RADS score is 3 of Criterion 1 and Criterion 3, 4 of Criterion 2 and Criterion 4. Related indicators were calculated, including the sensitivity, specificity, and area under curve (AUC). RESULTS: No significant differences between mp-MRI and Criterion 1 (AUC: 0.916 vs 0.912, p=0.498) were detected. The AUC for mp-MRI and Criterion 1 were both significantly higher than Criterion 2 (AUC: 0.916 vs 0.900, p=0.015; 0.912 vs 0.900, p<0.001), Criterion 3 (AUC: 0.916 vs 0.894, p<0.001; 0.912 vs 0.894, p=0.006), and Criterion 4 (AUC: 0.916 vs 0.896, p=0.004; 0.912 vs 0.896, p<0.001). CONCLUSIONS: mp-MRI and Criterion 1 have comparable diagnostic performance in diagnosing MIBC. Criterion 1, which is defined as the VI-RADS score is 2 if T2WI category 3 coupled with DWI category 2 and the VI-RADS score is 3 if T2WI category 3 coupled with DWI category 3, demonstrate superior diagnostic performance compared to other criteria. Download PPT Source of Funding: This study has received funding by the National Natural Science Foundation of China. (No: 82072832, 82273152) © 2024 by American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetails Volume 211Issue 5SMay 2024Page: e74 Advertisement Copyright & Permissions© 2024 by American Urological Association Education and Research, Inc.Metrics Author Information Qiang Lyu More articles by this author Xiao Yang More articles by this author Qiang Cao More articles by this author Peikun Liu More articles by this author Expand All Advertisement PDF downloadLoading ...