A Novel Strategy for the Development of Functional Foods to Improve Energy Metabolism Disorders: Stable Isotope-Resolved Metabolomics

With the change of people's dietary structures, obesity, diabetes, and other related chronic metabolic diseases characterized by energy metabolism disorders have become a public health problem worldwide. Stable isotope-resolved metabolomics (SIRM) as a novel technology to explore energy metabolism will certainly contribute to the development of functional foods to improve energy metabolism disorders. The purpose of this review is to elaborate on the technology processes of SIRM in the research of functional foods with improved energy metabolism disorders, and to promote the applications of this technology in functional food. The research strategies for functional foods for improving energy metabolism disorders were summarized. The progress of the application of SIRM on functional foods was elaborated and policy recommendations were also provided. In conclusion, the precise property of SIRM in revealing metabolic pathways will inevitably facilitate the development of functional foods in improving energy metabolism disorders.