Change in volumetric tumor growth rate after cytotoxic therapy is predictive of overall survival in recurrent glioblastoma.

Sonoko Oshima,Akifumi Hagiwara,Catalina Raymond,Chencai Wang,Nicholas S Cho,Jianwen Lu,Blaine S C Eldred,Phioanh L Nghiemphu,Albert Lai,Donatello Telesca,Noriko Salamon,Timothy F Cloughesy,Benjamin M Ellingson

Neuro-oncology advances（2023）

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摘要

A decrease in TGR in patients with PFS6, along with smaller baseline tumor volume, were associated with a significantly longer OS in rGBM treated with chemotherapy with or without radiation. Importantly, all patients that exhibited PFS6 also showed a measurable decrease in TGR.

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关键词

MRI, recurrent glioblastoma, survival, tumor growth rate

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