Drug reaction with eosinophilia and systemic symptoms (DRESS): clinical presentation and outcomes in people of color.

Fatima Bassir,Santiago Alvarez-Arango,Daniela Kroshinsky,Elizabeth Phillips,Adaeze J Ezeofor,Upeka Samarakoon,Suzanne V Blackley,Liqin Wang,Li Zhou,Kimberly G Blumenthal

The journal of allergy and clinical immunology. In practice（2023）

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摘要

Drug reaction with eosinophilia and systemic symptoms (DRESS) syndrome is a potentially life-threatening reaction characterized by fever, rash, lymphadenopathy, eosinophilia, and organ injury.1 DRESS is strongly associated with human leukocyte antigens (HLA) class I (eg, carbamazepine to HLA-B15:02), has an estimated incidence of 1 in 1,000 to 10,000 drug exposures, and carries a 5% to 10% fatality rate.1

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