Novel Meta-iodobenzylguanidine and Etoposide Complex: Physicochemical Characterization and Mathematical Modeling of Anticancer Activity

Omowumi Akinjole, Kathryn Menta,Abdullah Alsalhi,Majid Bani-Yaghoub,Bi-Botti Celestin Youan

AAPS PharmSciTech（2023）

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摘要

It is hypothesized that meta-iodobenzylguanidine (MIBG) complexation with etoposide (VP-16) will improve drug solubility and specificity towards BE(2)C neuroblastoma (NB) cells, 90

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关键词

decay rate,etoposide,meta-iodobenzylguanidine,morphology,neuroblastoma,solubility

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