Long-term Impact of Prenatal Famine on Differential DNA Methylation of Genes in the Serotonin Receptor Signalling Pathway in Adults
Neuroscience(2023)
摘要
•Genes of serotonin receptor signaling pathway are predominantly hypomethylated in adults born during the Chinese Famine.•The famine associated hypomethylation pattern in genes of serotonin receptor signaling pathway is highly sex-dependent.•Both HTR2A and HTR2C are significantly hypomethylated in females born during the Chinese Famine.
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关键词
fetal adversity,serotonin receptor signalling pathway,Chinese Famine,DNA methylation
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