Cyclo(His-Pro): A further step in the management of steatohepatitis.

Alessia De Masi,Xiaoxu Li,Dohyun Lee,Jongsu Jeon,Qi Wang,Seoyeong Baek, Onyu Park,Adrienne Mottis, Keno Strotjohann,Alexis Rapin,Hoe-Yune Jung,Johan Auwerx

JHEP reports : innovation in hepatology（2023）

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摘要

Considering the incidence and the lack of approved treatments, it is urgent to identify new strategies that prevent and manage NAFLD. CHP was effective in attenuating NAFLD progression in two animal models of the disease. Overall, our work points to CHP as a novel and effective strategy for the management of NAFLD, fuelling optimism for potential clinical studies.

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steatohepatitis,his-pro

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