CircSOD2 polarizes macrophages towards the M1 phenotype to alleviate cisplatin resistance in gastric cancer cells by targeting the miR-1296/STAT1 axis
Gene(2023)
摘要
•CircSOD2 was upregulated in M1 macrophages.•CircSOD2 enhanced M1 polarization.•Macrophages overexpressing circSOD2 enhanced the cisplatin effect.•CircSOD2 mediated STAT1 expression by interacting with miR-1296.
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关键词
circSOD2,Macrophage polarization,Cisplatin resistance,Gastric cancer
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