Biomarkers of the L-Arginine/Dimethylarginine/Nitric Oxide Pathway in People with Chronic Airflow Obstruction and Obstructive Sleep Apnoea.

Juliane Hannemann, Elin H Thorarinnsdottir,André F S Amaral,Edzard Schwedhelm,Lena Schmidt-Hutten,Heike Stang,Bryndis Benediktsdottir,Ingibjörg Gunnarsdóttir,Thórarinn Gislason,Rainer Böger

Journal of clinical medicine（2023）

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摘要

The plasma concentrations of ADMA and SDMA are elevated in COPD patients with concomitant intermittent hypoxaemia. This may account for impaired pulmonary NO production, enhanced pulmonary vasoconstriction, and disease progression.

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关键词

ADMA,SDMA,asymmetric dimethyl-arginine,chronic obstructive lung disease,intermittent hypoxaemia,symmetric dimethylarginine

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