The effect of bedtime versus morning dosing of antihypertensive drugs on the cardiovascular outcomes: a systematic review and meta-analysis of randomized controlled trials.

Mohamed Abuelazm,Othman Saleh,Majd M Albarakat,Basant Katamesh,Hassan Abdalshafy,Abdelrahman Mahmoud,Basel Abdelazeem

Journal of hypertension（2023）

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摘要

Evidence about the comparative efficacy of bedtime versus morning dosing of antihypertensives is still uncertain. However, bedtime dosing significantly reduced MI, which warrants more robust RCTs to validate.

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关键词

antihypertensive drugs,morning dosing,cardiovascular outcomes,bedtime,meta-analysis

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