Gut Microbiome in Patients With Early-Stage and Late-Stage Melanoma.

Russell G Witt,Samuel H Cass,Tiffaney Tran,Ashish Damania, Emelie E Nelson,Elizabeth Sirmans,Elizabeth M Burton,Manoj Chelvanambi,Sarah Johnson,Hussein A Tawbi,Jeffrey E Gershenwald, Michael A Davies,Christine Spencer,Aditya Mishra,Matthew C Wong,Nadim J Ajami,Christine B Peterson,Carrie R Daniel,Jennifer A Wargo,Jennifer L McQuade,Kelly C Nelson

JAMA dermatology（2023）

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摘要

The findings of this case-control study suggest that fecal microbiota profiles were significantly different among patients with melanoma and controls and between patients with early-stage and late-stage melanoma. Prospective investigations of the gut microbiome and changes that occur with disease progression may identify future microbial targets for intervention.

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melanoma,gut,early-stage,late-stage

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