Dynamic cytokines signature predicts survival outcome from severe Immune-related hepatitis with PD-1/PD-L1 blockade in lung cancer.

Liang Zeng,Yuling Zhou,Qinqin Xu,Zhe Huang,Lianxi Song,Zhan Wang, Li Deng, Yongsheng Wu, Yanchao Liang,Zhentian Liu,Xuan Gao,Xin Yi,Qiongzhi He,Xuefeng Xia,Haiyan Yang, Xing Zhang,Huan Yan,Haoyue Qin,Shaoding Lin,Nong Yang,Yongchang Zhang

Lung cancer (Amsterdam, Netherlands)（2023）

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摘要

Our study demonstrated the association between IL-1B overexpression and IRH susceptibility. Immune score and Euclidean distance of inflammatory cytokines may provide predictive value on the survival outcome from ≥ G3 IRH.

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关键词

Cytokines,Severe immune-related hepatitis,Lung cancer,Immunotherapy

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