Food insecurity screening and local food access: Contributions to nutritional outcomes among children and adults with cystic fibrosis in the United States

•Screening for food insecurity by CF care programs and local food access are independent predictors of nutritional status among children and adults with CF in the United States.•More frequent food insecurity screening is associated with less underweight in children with CF, and screening in writing (vs verbally) is associated with higher BMI in adults with CF.•Residence in a food desert is associated with higher odds of underweight in both children and adults with CF, as well as with lower BMI percentile in children with CF.•Standardized, evidence-based food insecurity screening across CF care programs and equitable food access are needed to optimize the nutritional outcomes of people with CF.