A fatal case of hemophagocytic lymphohistiocytosis due to neonatal lupus erythematosus
PEDIATRIC DERMATOLOGY(2024)
摘要
Neonatal lupus erythematosus (NLE) is an autoimmune disease caused by the passive transfer of autoantibodies from mother to child during pregnancy. A rare complication of NLE is hemophagocytic lymphohistiocytosis (HLH), a potentially life-threatening hyperinflammatory state more commonly associated with other rheumatologic disorders. Herein, we describe a fatal case of NLE-associated HLH.
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关键词
hemophagocytic lymphohistiocytosis,neonatal lupus erythematosus,SS-A/Ro antibody,SS-B/La antibody
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