Hexyl-(cuban-1-yl-methyl)-biguanide (HCB) suppresses N-glycosylation of immune checkpoint proteins B7-H3 and B7-H4, reverses tumor hypoxia, decreases intratumoral regulatory T cells, and increases intratumoral CD8+T cells in the ovarian dependent ER+HER2-SSM2ucd mammary cancer allograft model

CANCER RESEARCH(2023)

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