Blunted Coronary Flow Velocity Reserve After Anthracycline Therapy in Breast Cancer Patients

C. Yu, P. Jeyaprakash, K. Ozawa, S. Sivapathan, T. Negishi, D. Sabanathan, J. Park, J. Man, A. Vasista, R. Chittajallu, F. Pathan, K. Negishi

Heart, Lung and Circulation（2023）

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摘要

Anthracycline therapy (ANT) has been shown to damage the microcirculation in an animal model. There is limited evidence on the acute effect of ANT on coronary physiology in humans. Coronary flow velocity reserve (CFVR) by echocardiography provides an integrated assessment of coronary physiology. We sought to investigate the acute effect of ANT therapy in breast cancer patients on CFVR.

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coronary flow velocity reserve,anthracycline therapy,breast cancer patients,breast cancer,cancer patients

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