Obesity and statin use may impact the prevalence of diabetes in familial hypercholesterolaemia: A worldwide cross-sectional study by the EAS familial hypercholesterolaemia studies collaboration (FHSC)

Background and Aims: Statins are the cornerstone of treatment for patients with heterozygous familial hypercholesterolemia (HeFH) but increase the risk of diabetes mellitus in the general population. Obesity increases diabetes risk, with certain world regions reporting a high prevalence of obesity and diabetes in the general population. We explored the global prevalence of diabetes in adults with HeFH, and how obesity and statins may modify this risk.