Neutrophil extracellular traps and neutrophil-related mediators in human thyroid cancer.

Luca Modestino,Leonardo Cristinziano,Remo Poto,Annagioia Ventrici,Marialuisa Trocchia,Silvia Martina Ferrari,Poupak Fallahi,Sabrina Rosaria Paparo,Gianni Marone,Alessandro Antonelli,Gilda Varricchi,Maria Rosaria Galdiero

Frontiers in immunology（2023）

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摘要

MPO-DNA complexes, nucleosomes and, to some extent, CitH3 levels seem to correlate with malignancy and severity of progressive TC. Moreover, serum concentrations of PMN-related mediators (MPO, PTX3, GM-CSF) were increased in TCs compared to MNG and HCs.

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neutrophils, neutrophil extracellular traps, thyroid cancer, dedifferentiated thyroid cancer, NETs biomarkers

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