The impact of concurrent bacterial lung infection on immunotherapy in patients with non-small cell lung cancer: a retrospective cohort study.

Qiang Cao, Xinyan Wu,Yuquan Chen, Qi Wei,Yanwei You, Yi Qiang,Guangzhu Cao

Frontiers in cellular and infection microbiology（2023）

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摘要

NSCLC patients with BLI receiving ICI treatment show superior ORR and PFS compared to NSCLC alone without an increased CIP risk, positioning BLI as a predictive factor for improved outcomes in NSCLC patients receiving ICIs. However, the study has limitations including its retrospective nature and lacking data on BLI bacteria types and levels, which could influence therapy outcomes.

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关键词

non-small cell lung cancer, bacterial lung infection, microbial infection, lung cancer, retrospective cohort study, immunotherapy

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