Caplacizumab use for immune thrombotic thrombocytopenic purpura: the Milan thrombotic thrombocytopenic purpura registry.

Pasquale Agosti,Pasqualina De Leo,Marco Capecchi,Barbara Ferrari,Ilaria Mancini,Salvatore Gattillo,Silvia Maria Trisolini,Erminia Rinaldi,Gian Marco Podda, Lucia Prezioso,Prassede Salutari,Luca Facchini,Domenica Caramazza, Giulia Tolomelli,Andrea Artoni,Flora Peyvandi

Research and practice in thrombosis and haemostasis（2023）

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摘要

•Data on caplacizumab use for thrombotic thrombocytopenic purpura (TTP) in Italy are missing.•Twenty-six Italian patients were treated with caplacizumab for an acute immune TTP episode.•Caplacizumab was effective in treating acute TTP in the Italian real-world clinical setting.•Two major bleeds leading to drug discontinuation were observed.

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immune thrombotic thrombocytopenic purpura

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