Differential Response to Interleukin-1 Blockade With Anakinra on Cardiorespiratory Fitness in Patients With Heart Failure With Preserved Ejection Fraction Stratified According to Left Ventricular Ejection Fraction

HomeJournal of the American Heart AssociationJust AcceptedDifferential Response to Interleukin‐1 Blockade with Anakinra on Cardiorespiratory Fitness in Patients with HFpEF Stratified According to LVEF Open AccessRapid CommunicationPDF/EPUBAboutView PDFSections ToolsAdd to favoritesDownload citationsTrack citations ShareShare onFacebookTwitterLinked InMendeleyReddit Jump toOpen AccessRapid CommunicationPDF/EPUBDifferential Response to Interleukin‐1 Blockade with Anakinra on Cardiorespiratory Fitness in Patients with HFpEF Stratified According to LVEF Michele Golino, Francesco Moroni, Salvatore Carbone, Giuliana Corna, Cory Trankle, Hayley E. Billingsley, Marco G. Del Buono, Azita H. Talasaz, Georgia K. Thomas, Roberto De Ponti, Jeremy Turlington, Roshanak Markley, Ross Arena, Justin M. Canada, Benjamin Van Tassell and Antonio Abbate Michele GolinoMichele Golino https://orcid.org/0000-0003-0141-0127 , Pauley Heart Center, , Virginia Commonwealth University, , Richmond, , VA, , Department of Medicine and Surgery, , University of Insubria, , Varese, , Italy, Search for more papers by this author , Francesco MoroniFrancesco Moroni https://orcid.org/0000-0002-6101-1403 , Department of Internal Medicine, , University of Virginia, , Charlottesville, , VA, , Department of Medicine, Università Milano‐Bicocca, , Milan, , Italy, Search for more papers by this author , Salvatore CarboneSalvatore Carbone https://orcid.org/0000-0002-8163-0527 , Pauley Heart Center, , Virginia Commonwealth University, , Richmond, , VA, , Department of Kinesiology & Health Sciences, College of Humanities & Sciences, , Virginia Commonwealth University, , Richmond, , VA, Search for more papers by this author , Giuliana CornaGiuliana Corna https://orcid.org/0000-0002-2275-7448 , Pauley Heart Center, , Virginia Commonwealth University, , Richmond, , VA, Search for more papers by this author , Cory TrankleCory Trankle https://orcid.org/0000-0002-3891-7004 , Pauley Heart Center, , Virginia Commonwealth University, , Richmond, , VA, Search for more papers by this author , Hayley E. BillingsleyHayley E. Billingsley https://orcid.org/0000-0002-6239-467X , Pauley Heart Center, , Virginia Commonwealth University, , Richmond, , VA, , Department of Kinesiology & Health Sciences, College of Humanities & Sciences, , Virginia Commonwealth University, , Richmond, , VA, Search for more papers by this author , Marco G. Del BuonoMarco G. Del Buono https://orcid.org/0000-0002-7483-6164 , Department of Cardiovascular Medicine, Fondazione Policlinico Universitario A. Gemelli IRCCS, , Rome, , Italy, Search for more papers by this author , Azita H. TalasazAzita H. Talasaz https://orcid.org/0000-0003-1839-3685 , Department of Pharmacotherapy & Outcomes Sciences, , Virginia Commonwealth University, , Richmond, , VA, Search for more papers by this author , Georgia K. ThomasGeorgia K. Thomas https://orcid.org/0000-0002-8303-258X , Pauley Heart Center, , Virginia Commonwealth University, , Richmond, , VA, Search for more papers by this author , Roberto De PontiRoberto De Ponti https://orcid.org/0000-0003-3278-1721 , Department of Medicine and Surgery, , University of Insubria, , Varese, , Italy, Search for more papers by this author , Jeremy TurlingtonJeremy Turlington , Pauley Heart Center, , Virginia Commonwealth University, , Richmond, , VA, Search for more papers by this author , Roshanak MarkleyRoshanak Markley https://orcid.org/0000-0001-9676-3333 , Pauley Heart Center, , Virginia Commonwealth University, , Richmond, , VA, Search for more papers by this author , Ross ArenaRoss Arena https://orcid.org/0000-0002-6675-1996 , Department of Physical Therapy, College of Applied Health Sciences, , University of Illinois at Chicago, , Chicago, , IL, Search for more papers by this author , Justin M. CanadaJustin M. Canada https://orcid.org/0000-0002-1342-7463 , Pauley Heart Center, , Virginia Commonwealth University, , Richmond, , VA, Search for more papers by this author , Benjamin Van TassellBenjamin Van Tassell * Correspondence to: Antonio Abbate, PhD, Ruth C. Heede Professor of Cardiology, Robert M. Berne Cardiovascular Research Center, Department of Medicine, Division of Cardiovascular Medicine, University of Virginia – School of Medicine, 415 Lane Rd (MR5); PO Box 801394, Charlottesville, VA 22908‐1394. Email: E-mail Address: [email protected], 804‐828‐0513, Benjamin Van Tassell, PharmD, Department of Pharmacotherapy and Outcome Sciences, School of Pharmacy, Virginia Commonwealth University, 1200 E. Broad Street, Richmond, VA 23298. Email: E-mail Address: [email protected], 804‐828‐4583 https://orcid.org/0000-0003-0688-4487 , Pauley Heart Center, , Virginia Commonwealth University, , Richmond, , VA, , Department of Pharmacotherapy & Outcomes Sciences, , Virginia Commonwealth University, , Richmond, , VA, Search for more papers by this author and Antonio AbbateAntonio Abbate * Correspondence to: Antonio Abbate, PhD, Ruth C. Heede Professor of Cardiology, Robert M. Berne Cardiovascular Research Center, Department of Medicine, Division of Cardiovascular Medicine, University of Virginia – School of Medicine, 415 Lane Rd (MR5); PO Box 801394, Charlottesville, VA 22908‐1394. Email: E-mail Address: [email protected], 804‐828‐0513, Benjamin Van Tassell, PharmD, Department of Pharmacotherapy and Outcome Sciences, School of Pharmacy, Virginia Commonwealth University, 1200 E. Broad Street, Richmond, VA 23298. Email: E-mail Address: [email protected], 804‐828‐4583 https://orcid.org/0000-0002-1930-785X , Robert M. Berne Cardiovascular Research Center, and Division of Cardiology, , University of Virginia, , Charlottesville, , VA, Search for more papers by this author Originally published25 Aug 2023https://doi.org/10.1161/JAHA.123.031251Journal of the American Heart Association. 2023;0:e8820Footnotes* Correspondence to: Antonio Abbate, PhD, Ruth C. Heede Professor of Cardiology, Robert M. Berne Cardiovascular Research Center, Department of Medicine, Division of Cardiovascular Medicine, University of Virginia – School of Medicine, 415 Lane Rd (MR5); PO Box 801394, Charlottesville, VA 22908‐1394. Email: antonio.abbate@virginia.edu, 804‐828‐0513, Benjamin Van Tassell, PharmD, Department of Pharmacotherapy and Outcome Sciences, School of Pharmacy, Virginia Commonwealth University, 1200 E. Broad Street, Richmond, VA 23298. Email: bvantassell@vcu.edu, 804‐828‐4583#M Golino and F Moroni contributed equally to this article.This article has been accepted for publication and undergone full peer review but has not been through the copyediting, typesetting, pagination and proofreading process, which may lead to differences between this version and the Version of Record. Please cite this article as doi:10.1161/JAHA.121.031251 eLetters(0)eLetters should relate to an article recently published in the journal and are not a forum for providing unpublished data. Comments are reviewed for appropriate use of tone and language. Comments are not peer-reviewed. Acceptable comments are posted to the journal website only. Comments are not published in an issue and are not indexed in PubMed. Comments should be no longer than 500 words and will only be posted online. References are limited to 10. Authors of the article cited in the comment will be invited to reply, as appropriate.Comments and feedback on AHA/ASA Scientific Statements and Guidelines should be directed to the AHA/ASA Manuscript Oversight Committee via its Correspondence page.Sign In to Submit a Response to This Article Previous Back to top Next FiguresReferencesRelatedDetails Article InformationMetrics This article is protected by copyright. All rights reserved.This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.https://doi.org/10.1161/JAHA.123.031251PMID: 37624043 Manuscript receivedJune 4, 2023Manuscript acceptedAugust 18, 2023Originally publishedAugust 25, 2023 KeywordsInterleukin‐1Heart Failure, DiastolicCardiopulmonary Exercise TestAnakinraPDF download SubjectsHeart Failure