Non-coding RNAs in cancer immunotherapy: Predictive biomarkers and targets.

Clinical and translational medicine(2023)

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摘要
This review summarises important predictive ncRNA biomarkers that were reported in cancer patients treated with different immunotherapeutic modalities, including monoclonal antibodies, small molecule inhibitors, cancer vaccines and CAR-T cells. In addition, a concise discussion on forthcoming perspectives is provided, outlining technical approaches for the optimal utilisation of immunomodulatory ncRNA biomarkers as predictive tools and therapeutic targets.
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关键词
cancer immunotherapy, cancer vaccine, CAR-T cells, monoclonal antibodies, ncRNA biomarkers, ncRNA targets
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