Investigation of genomic mutations and their association with phenotypic resistance to new and repurposed drugs in Mycobacterium tuberculosis complex clinical isolates.

The Journal of antimicrobial chemotherapy(2023)

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摘要
More studies that correlate genotypic and phenotypic drug susceptibility data are needed to increase the knowledge base of mutations associated with resistance, in particular for pretomanid. Overall, this study contributes to the development of future mutation catalogues for M. tuberculosis complex isolates.
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关键词
<i>mycobacterium tuberculosis</i>,genomic mutations,phenotypic resistance
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