Endothelial damage inhibitor preserves the integrity of venous endothelial cells from patients undergoing coronary bypass surgery.

Timo Z Nazari-Shafti, Henriette Thau,Ema Zacharova,Christien M Beez,Vasileios Exarchos,Sebastian Neuber, Heike Meyborg, Kerstin Puhl, Corey Wittig,Robert Szulcek,Konrad Neumann,Costanza Giampietro, Katrin Krüger,Nikola Cesarovic,Volkmar Falk,Etem Caliskan,Hector Rodriguez Cetina Biefer,Maximilian Y Emmert

European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery（2023）

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摘要

EDI protects the connectivity and function of the SVG endothelium. Our data suggest that EDI can preserve focal adhesions in VECs during short-term storage after graft harvesting. This might explain the superiority of EDI in maintaining most of the endothelium in venous CABG surgery conduits.

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