Post COVID-19 Large Vessel Vasculopathy in a Previously Healthy Young Male.

The rising incidence of thrombosis post-coronavirus disease 2019 (COVID-19)[1] [2] places an increased burden on health care systems, as even young patients with prior asymptomatic severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection can suffer from delayed catastrophic thrombosis.[3] Mechanistically, post-COVID-19 thrombosis may arise from persistent thromboinflammation,[4] in turn arising from chronic hypercoagulability, endothelial dysfunction, inflammation,[5] neutrophil extracellular trap formation, and platelet hyperactivation,[6] which are detectable in some patients who have recovered from COVID-19. Here, we present radiological and histopathological evidence of chronic, large vessel vasculopathy associated with recurrent post-COVID-19 thrombosis in a young male.